{"id":1430,"date":"2024-04-30T17:42:34","date_gmt":"2024-04-30T09:42:34","guid":{"rendered":"https:\/\/www.dmdee.org\/archives\/1430"},"modified":"2024-04-30T17:42:34","modified_gmt":"2024-04-30T09:42:34","slug":"%e5%b0%bc%e4%ba%9a%e9%85%b0%e8%83%ba","status":"publish","type":"post","link":"https:\/\/www.dmdee.org\/archives\/1430","title":{"rendered":"\u5c3c\u4e9a\u9170\u80fa"},"content":{"rendered":"<p>    \t\t\t\t\t\t<img decoding=\"async\" src=\"http:\/\/staticv5.basechem.org\/img\/tupu\/old\/e727ba895680465e8f8e781038afd210.gif\" alt=\"\u5c3c\u4e9a\u9170\u80fa\u7ed3\u6784\u5f0f\"><\/p>\n<p>\u7ed3\u6784\u5f0f<\/p>\n<table class=\"summary-table table table-striped table-bordered\">\n<col width=\"90\" \/>\n<tbody>\n<tr>\n<th scope=\"row\">\u7269\u7ade\u7f16\u53f7<\/th>\n<td>014F<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\u5206\u5b50\u5f0f<\/th>\n<td>C16H18N4O2<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\u5206\u5b50\u91cf<\/th>\n<td>298.34<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\u6807\u7b7e<\/th>\n<td>\n<p>                        \u70df\u80bc\u9170\u80fa,<\/p>\n<p>                        \u5c3c\u4e9a\u62c9\u80fa,<\/p>\n<p>                        N-Benzyl-\u03b2-(isonicotinylhydrazino)propionamide,<\/p>\n<p>                        Pyridine-4-carboxylic 2-[2-(benzylcarbamoyl)ethyl]hydrazide,<\/p>\n<p>                        N-Isonicotinoyl-N&#039;-[\u03b2-(N-benzylcarboxamido)ethyl]hydrazine<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul class=\"nav nav-tabs\">\n<li class=\"active\"><a href=\"#bh\">\u7f16\u53f7\u7cfb\u7edf<\/a><\/li>\n<li><a href=\"#wx\">\u7269\u6027\u6570\u636e<\/a><\/li>\n<li><a href=\"#dl\">\u6bd2\u7406\u5b66\u6570\u636e<\/a><\/li>\n<li><a href=\"#st\">\u751f\u6001\u5b66\u6570\u636e<\/a><\/li>\n<li><a href=\"#fz\">\u5206\u5b50\u7ed3\u6784\u6570\u636e<\/a><\/li>\n<li><a href=\"#js\">\u8ba1\u7b97\u5316\u5b66\u6570\u636e<\/a><\/li>\n<li class=\"dropdown pull-right\">\n                    <a href=\"\" class=\"dropdown-toggle\" data-toggle=\"dropdown\">\u66f4\u591a <span class=\"caret\"><\/span><\/a><\/p>\n<ul class=\"dropdown-menu\" role=\"menu\">\n<li><a href=\"#xz\">\u6027\u8d28\u4e0e\u7a33\u5b9a\u6027<\/a><\/li>\n<li><a href=\"#zc\">\u8d2e\u5b58\u65b9\u6cd5<\/a><\/li>\n<li><a href=\"#hc\">\u5408\u6210\u65b9\u6cd5<\/a><\/li>\n<li><a href=\"#yt\">\u7528\u9014<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2 id=\"bh\">\u7f16\u53f7\u7cfb\u7edf<\/h2>\n<p><b>CAS\u53f7\uff1a<\/b>51-12-7<\/p>\n<p><b>MDL\u53f7\uff1a<\/b>MFCD00010106<\/p>\n<p><b>EINECS\u53f7\uff1a<\/b>200-079-3<\/p>\n<p><b>RTECS\u53f7\uff1a<\/b>NS1225000<\/p>\n<p><b>BRN\u53f7\uff1a<\/b>492941<\/p>\n<p><b>PubChem\u53f7\uff1a<\/b>24278185<\/p>\n<h2 id=\"wx\">\u7269\u6027\u6570\u636e<\/h2>\n<p><p>1.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u6027\u72b6\uff1a\u767d\u8272\u7ed3\u6676\u6027\u7c89\u672b\u3002\u5473\u5fae\u82e6\u3002<\/p>\n<p>2.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u5bc6\u5ea6\uff08g\/mL,25\/4\u2103\uff09\uff1a \u672a\u786e\u5b9a<\/p>\n<p>3.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u76f8\u5bf9\u84b8\u6c7d\u5bc6\u5ea6\uff08g\/mL,\u7a7a\u6c14=1\uff09\uff1a\u672a\u786e\u5b9a<\/p>\n<p>4.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u7194\u70b9\uff08\u00baC\uff09\uff1a &nbsp;152\uff5e153<\/p>\n<p>5.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u6cb8\u70b9\uff08\u00baC,\u5e38\u538b\uff09\uff1a\u672a\u786e\u5b9a<\/p>\n<p>6.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u6cb8\u70b9\uff08\u00baC,5.2kPa\uff09\uff1a\u672a\u786e\u5b9a<\/p>\n<p>7.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u6298\u5c04\u7387\uff1a\u672a\u786e\u5b9a<\/p>\n<p>8.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u95ea\u70b9\uff08\u00baC\uff09\uff1a\u672a\u786e\u5b9a<\/p>\n<p>9.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u6bd4\u65cb\u5149\u5ea6\uff08\u00ba\uff09\uff1a\u672a\u786e\u5b9a<\/p>\n<p>10.&nbsp;&nbsp;&nbsp; \u81ea\u71c3\u70b9\u6216\u5f15\u71c3\u6e29\u5ea6\uff08\u00baC\uff09\uff1a\u672a\u786e\u5b9a<\/p>\n<p>11.&nbsp;&nbsp;&nbsp; \u84b8\u6c14\u538b\uff08kPa,25\u00baC\uff09\uff1a\u672a\u786e\u5b9a<\/p>\n<p>12.&nbsp;&nbsp;&nbsp; \u9971\u548c\u84b8\u6c14\u538b\uff08kPa,60\u00baC\uff09\uff1a\u672a\u786e\u5b9a<\/p>\n<p>13.&nbsp;&nbsp;&nbsp; \u71c3\u70e7\u70ed\uff08KJ\/mol\uff09\uff1a\u672a\u786e\u5b9a<\/p>\n<p>14.&nbsp;&nbsp;&nbsp; \u4e34\u754c\u6e29\u5ea6\uff08\u00baC\uff09\uff1a\u672a\u786e\u5b9a<\/p>\n<p>15.&nbsp;&nbsp;&nbsp; \u4e34\u754c\u538b\u529b\uff08KPa\uff09\uff1a\u672a\u786e\u5b9a<\/p>\n<p>16.&nbsp;&nbsp;&nbsp; \u6cb9\u6c34\uff08\u8f9b\u9187\/\u6c34\uff09\u5206\u914d\u7cfb\u6570\u7684\u5bf9\u6570\u503c\uff1a\u672a\u786e\u5b9a<\/p>\n<p>17.&nbsp;&nbsp;&nbsp; \u7206\u70b8\u4e0a\u9650\uff08%,V\/V\uff09\uff1a\u672a\u786e\u5b9a<\/p>\n<p>18.&nbsp;&nbsp;&nbsp; \u7206\u70b8\u4e0b\u9650\uff08%,V\/V\uff09\uff1a\u672a\u786e\u5b9a<\/p>\n<p>19.&nbsp;&nbsp;&nbsp; \u6eb6\u89e3\u6027\uff1a\u6613\u6eb6\u4e8e\u9178\u6027\u6eb6\u5242\uff0c\u5fae\u6eb6\u4e8e\u6c34\u3002<\/p>\n<\/p>\n<h2 id=\"dl\">\u6bd2\u7406\u5b66\u6570\u636e<\/h2>\n<p>\n    \t\t1\u3001\u6025\u6027\u6bd2\u6027\uff1a\u5927\u9f20\u7ecf\u53e3LD50\uff1a1700mg\/kg\uff1b\u5927\u9f20\u8179\u8154LD50\uff1a760mg\/kg\uff1b\u5c0f\u9f20\u7ecf\u53e3LD50\uff1a590mg\/kg\uff1b\u5c0f\u9f20\u8179\u8154LD50\uff1a200mg\/kg\uff1b&nbsp;&nbsp; \u5154\u5b50\u8179\u8154LD50\uff1a&gt;150 mg\/kg2\u3001&nbsp;\u5176\u4ed6\u591a\u5242\u91cf\u6bd2\u6027\uff1a\u5927\u9f20\u7ecf\u53e3TDLo\uff1a54600mg\/kg26W-C3\u3001&nbsp;\u751f\u6b96\u6bd2\u6027\uff1a\u96cc\u6027\u5c0f\u9f20\u76ae\u4e0bTDLo\uff1a5045mg\/kg\uff0c6\u5929\u540e\u53d7\u5b554\u3001\u81f4\u7a81\u53d8\u6027\uff1a\u7a81\u53d8microorganismsTEST\u7cfb\u7edf\uff1a\u7ec6\u83cc-\u9f20\u4f24\u5bd2\u6c99\u95e8\u6c0f\u83cc\uff1a10ug\/plate\uff1bDNA\u7684repairTEST\u7cfb\u7edf\uff1a\u7ec6\u83cc-\u5927\u80a0\u6746\u83cc\uff1a27umol\/plate\uff1b\u7a81\u53d8\u6d4b\u8bd5\u7cfb\u7edf-\u800c\u4e0d\u662f\u5176\u4ed6specifiedTEST\u7cfb\u7edf\u7ec6\u83cc-\u67af\u8349\u82bd\u5b62\u6746\u83cc\uff1a10mmol\/L\uff1bDNA\u7834\u574f\uff1a\u5c0f\u9f20\u8179\u8154\uff1a2450umol\/kg\uff1b\u59d0\u59b9\u67d3\u8272\u4f53\u4ea4\u6362\uff1a\u5c0f\u9f20\u8179\u8154\uff1a435mg\/kg\n    \t<\/p>\n<h2 id=\"st\">\u751f\u6001\u5b66\u6570\u636e<\/h2>\n<p>\n    \t\t\u6682\u65e0\n    \t<\/p>\n<h2 id=\"fz\">\u5206\u5b50\u7ed3\u6784\u6570\u636e<\/h2>\n<p><p>1\u3001&nbsp; \u6469\u5c14\u6298\u5c04\u7387\uff1a83.57<\/p>\n<p>2\u3001&nbsp; \u6469\u5c14\u4f53\u79ef\uff08cm<sup>3<\/sup>\/mol\uff09\uff1a247.9<\/p>\n<p>3\u3001&nbsp; \u7b49\u5f20\u6bd4\u5bb9\uff0890.2K\uff09\uff1a667.0<\/p>\n<p>4\u3001&nbsp; \u8868\u9762\u5f20\u529b\uff08dyne\/cm\uff09\uff1a52.3<\/p>\n<p>5\u3001&nbsp; \u6781\u5316\u7387\uff0810-24cm3\uff09\uff1a33.13<\/p>\n<\/p>\n<h2 id=\"js\">\u8ba1\u7b97\u5316\u5b66\u6570\u636e<\/h2>\n<p><p>1\u3001&nbsp;&nbsp; \u758f\u6c34\u53c2\u6570\u8ba1\u7b97\u53c2\u8003\u503c\uff08XlogP\uff09\uff1a0.9<\/p>\n<p>2\u3001&nbsp;&nbsp; \u6c22\u952e\u4f9b\u4f53\u6570\u91cf\uff1a3<\/p>\n<p>3\u3001&nbsp;&nbsp; \u6c22\u952e\u53d7\u4f53\u6570\u91cf\uff1a4<\/p>\n<p>4\u3001&nbsp;&nbsp; \u53ef\u65cb\u8f6c\u5316\u5b66\u952e\u6570\u91cf\uff1a7<\/p>\n<p>5\u3001&nbsp;&nbsp; \u4e92\u53d8\u5f02\u6784\u4f53\u6570\u91cf\uff1a6<\/p>\n<p>6\u3001&nbsp;&nbsp; \u62d3\u6251\u5206\u5b50\u6781\u6027\u8868\u9762\u79ef\uff08TPSA\uff09\uff1a83.1<\/p>\n<p>7\u3001&nbsp;&nbsp; \u91cd\u539f\u5b50\u6570\u91cf\uff1a22<\/p>\n<p>8\u3001&nbsp;&nbsp; \u8868\u9762\u7535\u8377\uff1a0<\/p>\n<p>9\u3001&nbsp;&nbsp; \u590d\u6742\u5ea6\uff1a350<\/p>\n<p>10\u3001\u540c\u4f4d\u7d20\u539f\u5b50\u6570\u91cf\uff1a0<\/p>\n<p>11\u3001\u786e\u5b9a\u539f\u5b50\u7acb\u6784\u4e2d\u5fc3\u6570\u91cf\uff1a0<\/p>\n<p>12\u3001\u4e0d\u786e\u5b9a\u539f\u5b50\u7acb\u6784\u4e2d\u5fc3\u6570\u91cf\uff1a0<\/p>\n<p>13\u3001\u786e\u5b9a\u5316\u5b66\u952e\u7acb\u6784\u4e2d\u5fc3\u6570\u91cf\uff1a0<\/p>\n<p>14\u3001\u4e0d\u786e\u5b9a\u5316\u5b66\u952e\u7acb\u6784\u4e2d\u5fc3\u6570\u91cf\uff1a0<\/p>\n<p>15\u3001\u5171\u4ef7\u952e\u5355\u5143\u6570\u91cf\uff1a1<\/p>\n<\/p>\n<h2 id=\"xz\">\u6027\u8d28\u4e0e\u7a33\u5b9a\u6027<\/h2>\n<p>\n    \t\t\u6682\u65e0\n    \t<\/p>\n<h2 id=\"zc\">\u8d2e\u5b58\u65b9\u6cd5<\/h2>\n<p><p>&nbsp;\u672c\u54c1\u5e94\u5145\u6c29\u6c14\u5bc6\u5c01\u4e8e0\u2103\u4ee5\u4e0b\u4fdd\u5b58\u3002<\/p>\n<\/p>\n<h2 id=\"hc\">\u5408\u6210\u65b9\u6cd5<\/h2>\n<p><p>\u7531\u5f02\u70df\u9170\u80bc\u4e3a\u539f\u6599\u5236\u5f97\u3002<\/p>\n<\/p>\n<h2 id=\"yt\">\u7528\u9014<\/h2>\n<p>\n    \t\t\u4e00\u6c28\u6c27\u5316\u9176\uff08MAO\uff09\u6291\u5236\u5242\u3002\u533b\u836f\uff08\u6297\u6291\u90c1\u836f\uff09\u3002&nbsp; <\/p>\n<p>\u672c\u54c1\u4e3a\u5355\u80fa\u6c27\u5316\u9176\u6291\u5236\u5242\uff0c\u4f5c\u7528\u3001\u4e34\u5e8a\u7528\u9014\u548c\u4e0d\u826f\u53cd\u5e94\u4e0e\u4e59\u80bc\u76f8\u540c\u3002\u7528\u4e8e\u6cbb\u7597\u5404\u79cd\u6291\u90c1\u75c7\u3001\u7126\u8651\u548c\u6050\u6016\u75c7\uff0c\u4e5f\u53ef\u7528\u4e8e\u6cbb\u7597\u54bd\u75db\u3002<\/p>\n<\/p>\n<p>    \t\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/31-14.jpg\">https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/31-14.jpg<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.newtopchem.com\/archives\/44478\">https:\/\/www.newtopchem.com\/archives\/44478<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.bdmaee.net\/nnn-trimethylaminoethylethanolamine\/\">https:\/\/www.bdmaee.net\/nnn-trimethylaminoethylethanolamine\/<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.newtopchem.com\/archives\/44525\">https:\/\/www.newtopchem.com\/archives\/44525<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.bdmaee.net\/n-ethylmorpholine\/\">https:\/\/www.bdmaee.net\/n-ethylmorpholine\/<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.newtopchem.com\/archives\/745\">https:\/\/www.newtopchem.com\/archives\/745<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.newtopchem.com\/archives\/44583\">https:\/\/www.newtopchem.com\/archives\/44583<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.newtopchem.com\/archives\/952\">https:\/\/www.newtopchem.com\/archives\/952<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.newtopchem.com\/archives\/39808\">https:\/\/www.newtopchem.com\/archives\/39808<\/a><\/br>\u6269\u5c55\u9605\u8bfb<a href=\"https:\/\/www.bdmaee.net\/fascat-4201\/\">https:\/\/www.bdmaee.net\/fascat-4201\/<\/a><\/br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7ed3\u6784\u5f0f \u7269\u7ade\u7f16\u53f7 014F \u5206\u5b50\u5f0f C16H18N4O2 \u5206\u5b50\u91cf 298.34 \u6807\u7b7e \u70df\u80bc\u9170\u80fa, \u5c3c\u4e9a\u62c9\u80fa, N-Benzyl-\u03b2-(isonicotinylhydrazino)propionamide, Pyridine-4-carboxylic 2-[2-(benzylcarbamoyl)ethyl]hydrazi &#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[4],"tags":[948],"_links":{"self":[{"href":"https:\/\/www.dmdee.org\/wp-json\/wp\/v2\/posts\/1430"}],"collection":[{"href":"https:\/\/www.dmdee.org\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.dmdee.org\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.dmdee.org\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.dmdee.org\/wp-json\/wp\/v2\/comments?post=1430"}],"version-history":[{"count":0,"href":"https:\/\/www.dmdee.org\/wp-json\/wp\/v2\/posts\/1430\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.dmdee.org\/wp-json\/wp\/v2\/media?parent=1430"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.dmdee.org\/wp-json\/wp\/v2\/categories?post=1430"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.dmdee.org\/wp-json\/wp\/v2\/tags?post=1430"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}